The world's leader in noninvasive Peyronie's Disease treatment

Topical H100 ® Gel
Hope for Men with
Peyronie’s Disease

No Surgery - Just Results

Peyronie’s Disease Treatment That Works

In a randomized, double-blinded, placebo-controlled clinical trial, H100® showed statistically significant improvements in1:

H100® by Hybrid Medical is a breakthrough topical treatment offering new hope for men in the acute phase of Peyronie’s Disease. Clinically proven and easy to apply, H100® is changing what’s possible in non-invasive care.

What Makes
H100®
Different?

Patented formula with two plaque-modifying agents

Advanced topical delivery for targeted treatment

Backed by decades of medical experience and research

A Topical Treatment that Works!

H100® from Hybrid Medical™ is a patented and proprietary compound that combines an effective carrier agent with two plaque-modifying ingredients. When applied topically twice a day, it has been shown to help significantly lessen the curvature and penis pain associated with Peyronie’s disease and to help restore the quality of life for our patients1.

Why H100®?

Because Waiting a Year for Treatment Isn't
Good Enough

As a practicing urologist for over 30 years, I was frustrated by the lack of any new, effective, non-invasive treatment options for acute phase Peyronie’s disease (PD). Many men with acute phase PD are told to “see what happens” and come back in 6 to 12 months for a recheck. During that time, the PD often worsens. I developed non-invasive, topical H100® gel as a treatment to change the natural course of the disease in some men with PD, and to try and reduce the development of plaque and its associated symptoms of curvature, pain and decreased penile length. Ask your healthcare provider if H100®, combined with penile stretching exercises or penile traction, may be right for you.”

Learn About Peyronie's Disease & The H100® Treatment

What is Peyronie's Disease?

Learn about the symptoms & existing treatments of PD

What is Topical H100® Gel?

We'll tell you all about H100® & how it's revolutionary

Ready to take the next step—
or want to learn more?

Whether you’re ready to connect or still exploring if H100® is right for you, we’re here to help.

  1. J Twidwell, L Levine. Topical treatment for acute phase Peyronie’s disease utilizing a new gel, H-100: a randomized, prospective, placebo-controlled pilot study. International Journal of Impotence Research (2016) 28, 41–45; doi:10.1038/ijir.2015.22.
  2. Zemtsov A, Gaddis M, Montalvo-Lugo V. Moisturizing and Cosmetic Properties of Emu Oil: A Double Blind Study. Australas J Dermatol 1996; 37: 159–161.
  3. Qiu XW, Wang JH, Fang XW, Gong ZY, Li ZQ, Yi ZH. Anti-inflammatory activity and healing-promoting effects of topical application of emu oil on wound in scalded rats. [Article in Chinese]. Di Yi Jun Yi Da Xue Xue Bao 2005; 25: 407–410.
  4. Yoganathan S, Nicolosi R, Wilson T, Handelman G, Scollin P, Tao R et al. Antagonism of croton oil inflammation by topical emu oil in CD-1 mice. Lipids 2003; 38: 603–607.
  5. Soh J, Kawauchi A, Kanemitsu N, Naya Y, Ochial A, Naltoh Y et al. Nicardipine vs saline injection as treatment for Peyronie’s disease: a prospective, randomized, single-blind study. J Sex Med 2010; 7: 3743–3749.
  6. Riedl C, Sternig P, Galle G, Langmann F, Vcelar B, Vorauer K et al. Liposomal recombinant human superoxide dismutase for the treatment of Peyronie’s disease: a randomized placebo-controlled double-blind prospective clinical study. Eur Urol 2005; 48: 656–661.