The penis contains two tubes called “corpora” which fill with blood during an erection. Each corpora is long, tubular and has an outer casing of strong elastic tissue that stretches and expands during an erection. The inner portion of each corpora is filled with blood vessels.
With Peyronie’s disease, inflammation occurs in the wall of the corpora and during the healing process, scar tissue can form as a nodule or lump on the penis. Consequently, the area with scar tissue doesn’t stretch, so the penis curves and there can be pain in the penis.